Sen. Marco Rubio (R-Fla.) appears to be making significant moves toward a presidential run.

“He has told us to proceed as if he is running for president," a Rubio adviser told ABC News.

In this Jan. 8, 2014 file photo, Sen. Marco Rubio, R-Fla. speaks on Capitol Hill in Washington. (AP Photo/J. Scott Applewhite, File)

On Friday and Saturday, he will meet with several hundred supporters and donors at a Miami hotel to discuss his future political plans.

According to ABC, he will skip all Senate votes next week for fundraising events in California, Texas and Chicago.

Additionally, he's bringing on board Anna Rogers, currently the finance director for the Karl Rove-founded American Crossroads, to work on his political action committee.

A senior aide told ABC that the tour for Rubio's book, "American Dreams: Restoring Economic Opportunity for Everyone" will focus heavily on key presidential contest states, including Iowa, New Hampshire and South Carolina.

Rubio has been a voice in recent weeks against the U.S. easing tensions with Cuba.