WATCH: Bill Maher makes Seth MacFarlane go silent with COVID rant

Seth MacFarlane may know how to create a hit show, but he doesn’t know much when it comes to the COVID-19 vaccine — which he made clear in his tense appearance on "Club Random with Bill Maher."

Maher, on the other hand, showed that the propaganda from the past few years hasn’t gotten to him.

“If you already had the disease you have natural immunity,” Maher told MacFarlane, who fired back, “That was debunked, though.”

“It’s not debunked,” Maher responded.

“Don’t you know people who’ve had COVID four or five times? I do. That’s not natural immunity. There’s no immunity there,” MacFarlane continued before Maher noted that those who keep getting COVID have probably “had too many vaccines.”

MacFarlane then questioned Maher on whether or not he believes the vaccine gave people COVID.

“There’s nothing unscientific about the fact that the vaccine, which does weaken you in order to strengthen you, but while you were in a weakened state — yes,” Maher answered.

Maher then went on to explain that everyone is different, and while some people who were in situations of compromised health already needed the shot — others didn’t.

He explained to MacFarlane that he’s “assuming that all people are alike.”

“And that is one of the giant fallacies in your way of thinking, we are not all alike,” he added.

“Djokovic didn’t need it. Aaron Rodgers didn’t need it,” Maher said. “You completely want to shut your eyes to the fact that there are repercussions to all medical interventions including a vaccine!”

Want more from Dave Rubin?

To enjoy more honest conversations, free speech, and big ideas with Dave Rubin, subscribe to BlazeTV — the largest multi-platform network of voices who love America, defend the Constitution, and live the American dream.